Reference Gene

Gene name Alias Species Exons Type Paralogs EC number OMIM
KRT77 keratin 77 K1B , KRT1B Homo sapiens 10 protein-coding KRT8 , KRT6C , KRT6B , KRT6A , KRT80 , KRT74 , KRT71 , KRT72 , KRT73 , KRT78 , KRT4 , KRT79 , KRT76 , KRT3 , KRT2 , KRT1 , KRT75 , KRT5 , KRT85 , KRT86 , KRT81 , KRT83 , KRT84 , KRT82 , KRT7 611158

Summary

Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes an epithelial keratin that is expressed in the skin and eccrine sweat glands. The type II keratins are clustered in a region of chromosome 12q13.[provided by RefSeq, Jun 2009]

GeneOntology

Gene Loss events - KRT77 (12 results)

GL_ID Species Order Gene Loss Mechanism Loss Type Lineage Specific Citation
GL_0BIFCT Orcinus orca Artiodactyla Gene deletion Full Cetacea 10.1016/j.cub.2021.02.057
GL_6AQUGL Orcinus orca Artiodactyla Gene deletion Full No 10.1186/s12983-017-0225-x
GL_6RD9H4 Balaena mysticetus Artiodactyla Gene deletion Full No 10.1186/s12983-017-0225-x
GL_BSCFRS Physeter catodon Artiodactyla Gene deletion Full No 10.1186/s12983-017-0225-x
GL_DRQEPD Balaenoptera acutorostrata Artiodactyla Gene deletion Full No 10.1186/s12983-017-0225-x
GL_GVAOSZ Hexaprotodon liberiensis Artiodactyla LOF (frameshift, premature stop, ss) Full Hippopotamidae 10.1016/j.cub.2021.02.057
GL_IQ3OLK Balaenoptera acutorostrata Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.1016/j.cub.2021.02.057
GL_JG41BL Hippopotamus amphibius Artiodactyla LOF (frameshift, premature stop, ss) Full Hippopotamidae 10.1016/j.cub.2021.02.057
GL_SS6ZFU Tursiops truncatus Artiodactyla Gene deletion Full Cetacea 10.1016/j.cub.2021.02.057
GL_T3XLXL Neophocaena asiaeorientalis asiaeorientalis Artiodactyla Gene deletion Full No 10.1186/s12983-017-0225-x