Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| KRT23 keratin 23 | K23 , CK23 , HAIK1 | Homo sapiens | 10 | protein-coding | BFSP2 , KRT18 , KRT24 , KRT33B , KRT34 , LOC100653049 , KRT33A , KRT31 , KRT40 , KRT38 , KRT37 , KRT39 , KRT35 , KRT32 , KRT36 , KRT19 , KRT27 , KRT28 , KRT25 , KRT26 , KRT10 , KRT12 , KRT17 , KRT20 , KRT16 , KRT14 , KRT9 , KRT15 , KRT13 | 606194 |
Summary
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
GeneOntology
Gene Loss events - KRT23 (4 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_5HHJ2S | Physeter catodon | Artiodactyla | Other | Full | No | 10.1186/s12983-017-0225-x |
| GL_JK6DKK | Orcinus orca | Artiodactyla | Gene deletion | Full | No | 10.1186/s12983-017-0225-x |
| GL_KUSTWL | Neophocaena asiaeorientalis asiaeorientalis | Artiodactyla | Gene deletion | Full | No | 10.1186/s12983-017-0225-x |
| GL_SBCUPD | Lipotes vexillifer | Artiodactyla | Gene deletion | Full | No | 10.1186/s12983-017-0225-x |