Reference Gene

Gene name Alias Species Exons Type Paralogs EC number OMIM
KRT27 keratin 27 KRT25C , K25IRS3 Homo sapiens 8 protein-coding BFSP2 , KRT18 , KRT24 , KRT23 , KRT33B , KRT34 , LOC100653049 , KRT33A , KRT31 , KRT40 , KRT38 , KRT37 , KRT39 , KRT35 , KRT32 , KRT36 , KRT19 , KRT28 , KRT25 , KRT26 , KRT10 , KRT12 , KRT17 , KRT20 , KRT16 , KRT14 , KRT9 , KRT15 , KRT13 616676

Summary

This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2009]

GeneOntology

Gene Loss events - KRT27 (6 results)

GL_ID Species Order Gene Loss Mechanism Loss Type Lineage Specific Citation
GL_IA0DML Orcinus orca Artiodactyla Gene deletion Full No 10.1186/s12983-017-0225-x
GL_LFHJNT Balaenoptera acutorostrata Artiodactyla Gene deletion Full No 10.1186/s12983-017-0225-x
GL_MSGDYT Tursiops truncatus Artiodactyla Gene deletion Full No 10.1186/s12983-017-0225-x
GL_OFGKVY Balaena mysticetus Artiodactyla Gene deletion Full No 10.1186/s12983-017-0225-x
GL_PNXOSE Neophocaena asiaeorientalis asiaeorientalis Artiodactyla Gene deletion Full No 10.1186/s12983-017-0225-x
GL_ZINJMM Lipotes vexillifer Artiodactyla Gene deletion Full No 10.1186/s12983-017-0225-x