Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| DPEP2 dipeptidase 2 | MBD2 | Homo sapiens | 13 | protein-coding | DPEP3 , DPEP1 | 3.4.13.19 | 609925 |
Summary
DPEP2 belongs to the membrane-bound dipeptidase (EC 3.4.13.19) family. These enzymes hydrolyze a variety of dipeptides, including leukotriene D4, the beta-lactam ring of some antibiotics, and cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation (Habib et al., 2003 [PubMed 12738806]).[supplied by OMIM, Mar 2008]
GeneOntology
Gene Loss events - DPEP2 (1 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_K6OPOF | Physeter catodon | Artiodactyla | Other | Full | Physeter | 10.1093/gbe/evx187 |