Reference Gene

Gene name Alias Species Exons Type Paralogs EC number OMIM
MS4A5 membrane spanning 4-domains A5 TETM4 , CD20L2 , CD20-L2 Homo sapiens 5 protein-coding MS4A14 , MS4A18 , MS4A10 , MS4A12 , MS4A15 , MS4A2 , MS4A7 , MS4A6A , MS4A6E , MS4A1 , MS4A13 , MS4A8 , MS4A3 , MS4A4A 606499

Summary

This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. Though this member is not expressed in hematopoietic cells specifically, it may be involved in signal transduction like many of its related family members. The gene encoding this protein is localized to 11q12, among a cluster of family members. [provided by RefSeq, Jul 2008]

GeneOntology

Gene Loss events - MS4A5 (4 results)

GL_ID Species Order Gene Loss Mechanism Loss Type Lineage Specific Citation
GL_QBZOKU Tursiops truncatus Artiodactyla Other Full Cetacea 10.1126/sciadv.aaw6671
GL_R9TLRZ Orcinus orca Artiodactyla Other Full Cetacea 10.1126/sciadv.aaw6671
GL_SRGM5C Balaenoptera acutorostrata Artiodactyla Other Full Cetacea 10.1126/sciadv.aaw6671
GL_TKQCBF Physeter catodon Artiodactyla Other Full Cetacea 10.1126/sciadv.aaw6671