Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| CYP4X1 cytochrome P450 family 4 subfamily X member 1 | CYPIVX1 | Homo sapiens | 15 | protein-coding | CYP19A1 , CYP24A1 , CYP4V2 , CYP27C1 , CYP27B1 , CYP27A1 , CYP4F11 , CYP4F12 , CYP4F2 , CYP4F8 , CYP4F3 , CYP4F22 , CYP4A22 , CYP4A11 , CYP4Z1 , CYP4B1 | 1.14.14.1 | 614999 |
Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes and is located within a cluster of genes belonging to this superfamily on chromosome 1. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The expression pattern of a similar rat protein suggests that this protein may be involved in neurovascular function in the brain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
GeneOntology
Gene Loss events - CYP4X1 (4 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_9CXEPM | Balaenoptera acutorostrata | Artiodactyla | Other | Full | Cetacea | 10.1126/sciadv.aaw6671 |
| GL_IZE3PW | Tursiops truncatus | Artiodactyla | Other | Full | Cetacea | 10.1126/sciadv.aaw6671 |
| GL_LRHMLU | Orcinus orca | Artiodactyla | Other | Full | Cetacea | 10.1126/sciadv.aaw6671 |
| GL_LTHJDB | Physeter catodon | Artiodactyla | Other | Full | Cetacea | 10.1126/sciadv.aaw6671 |